Is Two out of Three Enough for ABCG1?

Is two out of three enough for ABCG1?

Macrophages have the right tools to synthesize all the free cholesterol they need. If macrophages also could degrade cholesterol when they have too much, the concept of in vivo reverse cholesterol transport (RCT) would be irrelevant. Fortunately for those of us who do research in this area, the ability of macrophages to closely regulate their cellular cholesterol levels is accomplished not by c...

Glycine Receptor Activation: When Three Out of Five Is Enough

The prototypic member of the acetylcholine receptor family, the muscle nicotinic receptor, is a heteromeric complex with five subunits but only two ligand-binding sites. However, some members of this receptor superfamily are homomeric, containing five seemingly identical binding sites. Whether activation actually requires binding of five agonist molecules in this situation is unclear. Such ques...

Reinforcement learning from comparisons: Three alternatives is enough, two is not

The paper deals with the problem of finding the best alternatives on the basis of pairwise comparisons when these comparisons need not be transitive. In this setting, we study a reinforcement urn model. We prove convergence to the optimal solution when reinforcement of a winning alternative occurs each time after considering three random alternatives. The simpler process, which reinforces the w...

is hymenotomy enough for treatment of imperforated hymen?

Measuring Preattentive Processes: When is Pop-out Not Enough?

Three behavioural tasks (standard visual search, multiple target search, and numberdiscrimination)weretestedwithavariety of stimuli relevanttotwo-stage theories of vision. One purpose was to compare the two versions of the search task; a second was to explore the relations between processes of search and enumeration. The two search tasks were quite consistent overall, with strong correlations b...